Alex de Mendoza

Lecturer, Queen Mary University of London
  • Queen Mary University of London
  • Members
  • United Kingdom

About Alex de Mendoza

Interested in the evolution of gene regulatory mechanisms in animals and unicellular eukaryotes.

Subject

Phylogenetics Molecular evolution Evolutionary genetics

Intro Content

Contributor Nature Eco Evo

A brain “zoo” reveals how a non-canonical form of DNA methylation emerged

Most animals use DNA methylation at CG dinucleotides to regulate gene expression. However, we found that a non-CG form of DNA methylation was a much later addition to the epigenetic code that regulates brain transcriptional programs in vertebrates.

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Behind the paper