- Queen Mary University of London
- Members
- United Kingdom
About Alex de Mendoza
Interested in the evolution of gene regulatory mechanisms in animals and unicellular eukaryotes.
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Intro Content
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Nature Eco Evo
A brain “zoo” reveals how a non-canonical form of DNA methylation emerged
Most animals use DNA methylation at CG dinucleotides to regulate gene expression. However, we found that a non-CG form of DNA methylation was a much later addition to the epigenetic code that regulates brain transcriptional programs in vertebrates.